Hello fellow bio-hackers! This is your online hub for all things bio-hacking. We're a community of people obsessed with optimizing our biology and taking control of our physical and mental performance. Here, we share tips, knowledge and experiences on the latest science and tech to help each other reach our full potential. Join us and let's maximize our biology together! ⚙️🧬🧠
“The convergence of evidence from large cohort studies and small randomized controlled trials supports the conclusion that moderate caffeine or coffee consumption (up to 400 mg/d caffeine or ≈3–5 cups...
www.medpagetoday.com
American Heart Association Weighs In on Coffee Drinking
Scientific statement reviewed mostly observational evidence about safety and possible benefits
TS
Todd Smithcommented · 3 weeks ago
Speaking of coffee I’ve been LOVING Praxanthine. It’s a downstream metabolite of caffeine that is far less habit-forming, tolerance-building, and the best part — half-life is only about 3 hours, so it does not affect #Sleep at all. Also, no jitters and far less anxiety-inducing. I’ve been taking about 200mg first thing in the morning and then about 160mg at about 1pm. I still drink decaf coffee all day. It’s so good I can’t believe it’s not way more popular. #Biohackers Connect https://en.wikipedia.org/wiki/Paraxanthine
Exceptionally good writeup on LDL. TL;DR:
• Lowering LDL is not a panacea, esp with statins. PCSK9 etc is prob better.
• The root of all evil is sugar & simple carbs. (surprise!) If you jus...
open.substack.com
Why does your body make cholesterol if it kills us?
Exploring what I think is going on with the #1 killer of Americans, statins and LDL
Computational biology is so exciting. You can just design proteins that can fix all your shit. Totally 🤯
This thing is this is not even crazy hard to do anymore. #Healthspan Advocates #Leverage Your ...
Ta
Tasiacommented · last month
always blew my mind to wonder like what exactly determines the patterns on a turtle shell or whatever - seems like the morphogenesis papers are kinda like "this mathematically is possible/conceivable as a way that DNA could represent things" but we're still a long way from concretely understanding it... at least thats as much as i know
sorry if this is a dumb question, but where do y'all land on whether seed oils are bad?as far as i can tell the research doesnt seem conclusive, but it seems like people go nuts over them.
anyone here...
Recent #Artificial Intelligence#Gadgets startups have struggled to convert hype to usable gadgets. But one private-market tech company is not having a hard time driving revenue. It’s Oura, best know...
www.bloomberg.com
Oura Nears $500 Million in Annual Revenue and Readies New Ring
Oura Health Oy, a Finnish health technology company known for its fitness-tracking rings, will see annual sales double this year to roughly $500 million and expects “healthy” growth in 2025.
JC
Jerome Codycommented · 21 hours ago
Oura Inc., the company that sells rings that track people’s health and activities, has turned into an enormously profitable enterprise. Its IPO filing, disclosed on Thursday, showed that it generated $262 million in free cash flow in the nine months ending June 30. #Gadgets Oura is also growing quickly, lifting revenue 74% to $1.2 billion in the same period. The number of rings sold hit 3.1 million in the nine month period, up from 1.8 million a year earlier, while the number of paying members doubled to five million. Paying members get extra benefits. Oura is one of the highest profile examples of wearables startups, cashing in on consumers’ desire to track their health in detail. Oura is competing with Apple’s watch, Google’s Fitbit as well as other standalone firms such as Whoop. https://techcrunch.com/2026/09/03/oura-files-to-go-public/
Telling kids they're smart may actually hurt their performance:
- Kids praised for intelligence ("you're so smart") scored lower on follow-up problems
- Kids praised for effort scored higher on the sa...
Na
Natecommented · 6 days ago
My parents made me do the dishes every day until I left for college, and whenever I was home. Now as an adult, washing dishes by hand is extremely cathartic.
Cancer treatment could face landmark moment with promising vaccine
A therapy using the same mRNA technology in coronavirus vaccines showed positive results in a trial for skin cancer patients, drugmakers Moderna and Merck said.
Na
Natecommented · 2 weeks ago
Why this is a big deal: this mRNA therapy instructs the body to produce the specific fingerprints of the person's tumor and trains the immune system to hunt and kill it. First time in a Phase 3 trial. One way cancer grows is by hiding from the immune system and turning off attacking T-cells. This mRNA therapy provides the tumor's genetic fingerprint so that the immune system can train T-cells to identify the cancer. Keytruda then removes the brakes that cancer had put on the T-cells enabling them to eliminate the cancer.
Speaking of coffee I’ve been LOVING Praxanthine. It’s a downstream metabolite of caffeine that is far less habit-forming, tolerance-building, and the best part — half-life is only about 3 hours, so it...
en.wikipedia.org
Paraxanthine
Paraxanthine, also known as 1,7-dimethylxanthine, is an isomer of theophylline and theobromine, two well-known stimulants found in coffee, tea, and chocolate. It is a member of the xanthine family of alkaloids, which also includes theophylline and theobromine in addition to caffeine.
SM
Sam Mendozacommented · 3 weeks ago
Big fan. Last I bought the powder from Everychem, but there are a couple of brands on Amazon also.
The science is intriguing but incomplete. Animal data is promising. Human data is minimal.
Regulation is weak.The market is messy. Until proper clinical trials are conducted:
Caveat emptor — buyer be...
www.economist.com
Can peptides give you superpowers?
The “Wolverine stack” is supposed to boost healing and recovery
If you thought coffee, popcorn, or beer were the last dominos to fall in the race to protein-ify everything, think again. The rising (pep)tide has now come for America's favorite toaster pastry: Pop-T...
sherwood.news
Pop-Tarts, Doritos, and Uncrustables have joined the protein craze taking over America’s snack aisle
Food giants are catching up with the latest diet obsession....