Hello fellow bio-hackers! This is your online hub for all things bio-hacking. We're a community of people obsessed with optimizing our biology and taking control of our physical and mental performance. Here, we share tips, knowledge and experiences on the latest science and tech to help each other reach our full potential. Join us and let's maximize our biology together! ⚙️🧬🧠
I completed my mid-year Function lab test and was certain I’d feel disheartened by my results because healthy diet and consistent exercise left the chat over the last month+… I’m so confused that I’m ...
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Sam Mendozacommented · last week
Biology is complicated. Perhaps see on your next retest; could be delayed, an outlier result, a genuinely bad test, or something changed that you’re not considering.
“The convergence of evidence from large cohort studies and small randomized controlled trials supports the conclusion that moderate caffeine or coffee consumption (up to 400 mg/d caffeine or ≈3–5 cups...
www.medpagetoday.com
American Heart Association Weighs In on Coffee Drinking
Scientific statement reviewed mostly observational evidence about safety and possible benefits
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Todd Smithcommented · 2 months ago
Speaking of coffee I’ve been LOVING Praxanthine. It’s a downstream metabolite of caffeine that is far less habit-forming, tolerance-building, and the best part — half-life is only about 3 hours, so it does not affect #Sleep at all. Also, no jitters and far less anxiety-inducing. I’ve been taking about 200mg first thing in the morning and then about 160mg at about 1pm. I still drink decaf coffee all day. It’s so good I can’t believe it’s not way more popular. #Biohackers Connect https://en.wikipedia.org/wiki/Paraxanthine
Telling kids they're smart may actually hurt their performance:
- Kids praised for intelligence ("you're so smart") scored lower on follow-up problems
- Kids praised for effort scored higher on the sa...
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Sam Mendozacommented · 3 weeks ago
I don't think you have as much control over how your kids turn out as you think
sorry if this is a dumb question, but where do y'all land on whether seed oils are bad?as far as i can tell the research doesnt seem conclusive, but it seems like people go nuts over them.
anyone here...
Recent #Artificial Intelligence#Gadgets startups have struggled to convert hype to usable gadgets. But one private-market tech company is not having a hard time driving revenue. It’s Oura, best know...
www.bloomberg.com
Oura Nears $500 Million in Annual Revenue and Readies New Ring
Oura Health Oy, a Finnish health technology company known for its fitness-tracking rings, will see annual sales double this year to roughly $500 million and expects “healthy” growth in 2025.
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Sam Mendozacommented · 10 hours ago
Hardware is hard, but calling Oura the next Peloton ignores how much people hate taking off their ring vs. sitting on an exercise bike. 9x sales is steep, but bet against consumer wellness habits at your own risk! 💍📊 #Sleep #Gadgets #The Most Important Thing #Biohackers Connect Oura, one of the leaders in health-related wearables, has made quite the name for itself in the past few years. Revenue more than doubled in its fiscal 2025, ending last September, to $907.9 million and jumped another 74% in the nine months ending June of this year. Oura is generating real cash—$100 million in fiscal 2025. But we’ve been here before. As Arete Research analyst Richard Kramer notes, Oura has parallels to other “single product–plus-subscription models that didn’t end well,” such as Peloton, GoPro and Fitbit. Take GoPro, which went public in 2014, when its sales were surging. In 2013, revenue had nearly doubled to $985.7 million, expanding 41% in 2014. GoPro was also making real money—$84 million in 2013, dipping a bit in 2014. Investors were wary, although one half-witted columnist (OK, it was me) took a stupidly contrarian view in this 2015 piece suggesting GoPro still had potential for growth. I couldn’t have been more wrong. GoPro’s revenue peaked in 2015 at $1.6 billion and started shrinking after that, hitting $651 million in 2025. Its stock price fell from around $50 to $60 in mid-2015 to 60 cents last month. On Sept. 1, GoPro announced it was merging with an optical photonics firm in a deal that will give its shareholders $1.14 in cash and a tiny amount of equity in the newly combined company. GoPro’s problem is that, like Oura, it’s a niche product in a market where there are lots of alternatives—most obviously smartphones whose cameras just keep getting better. Oura is in the same boat. There are lots of rival wearables—including the Apple Watch and a $99 wrist tracker recently introduced by Google. And Oura’s rings aren’t cheap at $349 or more. Oura’s shares also don’t look cheap. At the midpoint of its tentative pricing range, Oura looks to be valued at around nine times this year’s estimated revenue—assuming the growth it reported for the first nine months carries through into the fourth quarter. That multiple is roughly where GoPro traded at its peak in 2014, according to Koyfin data. But for most of the past decade, GoPro shares traded at between 0.3 and one time forward sales. Sonos, another niche hardware maker, currently trades at 1.2 times forward sale. The only hardware stock that trades around nine times sales is Apple. And there’s no comparison between Apple and Oura. Investors might be better off avoiding Oura. https://www.theinformation.com/newsletters/the-briefing/oura-may-healthiest-ipo?rc=gzsl71
Just signed up for Function Health (Black Friday FTW 😉). is there any must-do add-ons for the first time? thinking I can add those at the 6 month screening.
https://www.functionhealt..
#Health...
www.functionhealth.com
Function | 100 Healthy Years
It’s time you own your health. Function includes 160+ lab tests and personalized protocols for instant action. Tracked over time in one secure place.
Nica took a screenshot of this post and discussion · 2 weeks ago
Cancer treatment could face landmark moment with promising vaccine
A therapy using the same mRNA technology in coronavirus vaccines showed positive results in a trial for skin cancer patients, drugmakers Moderna and Merck said.
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Natecommented · last month
Why this is a big deal: this mRNA therapy instructs the body to produce the specific fingerprints of the person's tumor and trains the immune system to hunt and kill it. First time in a Phase 3 trial. One way cancer grows is by hiding from the immune system and turning off attacking T-cells. This mRNA therapy provides the tumor's genetic fingerprint so that the immune system can train T-cells to identify the cancer. Keytruda then removes the brakes that cancer had put on the T-cells enabling them to eliminate the cancer.
Speaking of coffee I’ve been LOVING Praxanthine. It’s a downstream metabolite of caffeine that is far less habit-forming, tolerance-building, and the best part — half-life is only about 3 hours, so it...
en.wikipedia.org
Paraxanthine
Paraxanthine, also known as 1,7-dimethylxanthine, is an isomer of theophylline and theobromine, two well-known stimulants found in coffee, tea, and chocolate. It is a member of the xanthine family of alkaloids, which also includes theophylline and theobromine in addition to caffeine.
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Sam Mendozacommented · last month
Big fan. Last I bought the powder from Everychem, but there are a couple of brands on Amazon also.
If you thought coffee, popcorn, or beer were the last dominos to fall in the race to protein-ify everything, think again. The rising (pep)tide has now come for America's favorite toaster pastry: Pop-T...
sherwood.news
Pop-Tarts, Doritos, and Uncrustables have joined the protein craze taking over America’s snack aisle
Food giants are catching up with the latest diet obsession....